I'm not a huge fan of Ubuntu, but its a pretty simple distro for quick installs.
I plan to post my tweaks here that I make to a default install so that I can actually deal with using it on a daily basis.
(UPDATE) I have since quit using Ubuntu altogether (in favor of Gentoo). My mother still runs it though.
Ubuntu 8.10 Upgrade
Here is a good reason not to install Ubuntu :P
After upgrading from inside of a current 8.04 install, the system reboot and then hangs with a kernel panic. Turns out that the grub menu was incorrectly updated and that an initrd image was not created. Execute the following steps:
System Bell / Beep
This is SUPER annoying...
/etc/modprobe.d/blacklistVi / ViM
Turns out that Ubuntu doesn't come with the full Vi install...
Fonts / Nvidia / DPI
After installing the binary/closed Nvidia driver, some fonts become FAR to large. A good example is at the GDM login screen. The username and password field characters don't even fit anymore!
Option "UseEdidDpi" "false" Option "Dpi" "92 x 92"
Nvidia Powermizer
http://tutanhamon.com.ua/technovodstvo/NVIDIA-UNIX-driver/
Quick example: in xorg.conf: Option "RegistryDwords" "PowerMizerEnable=0x1; PerfLevelSrc=0x2222; PowerMizerDefault=0x3; PowerMizerDefaultAC=0x1"
This sets minimum power when battery operated and maximum when AC powered.
Also, to manually set a power level, in xorg.conf: Option "RegistryDwords" "PowerMizerLevel=0x3"
CPU Throttling
A CPU speed applet can be added to the menu bar that reports the current cpu speed. However, by default you cannot manually set the speed or the mode (conservative, on-demand, etc).